Blood screening tests could predict Alzheimer's disease
For people with Alzheimer's disease, extensive neuronal loss occurs before symptoms of the disease begin to appear. As the brain engages in daily tasks, it repeatedly produces and clears away a sticky protein called amyloid beta. Some of the amyloid beta gets washed away in the blood and cerebrospinal fluid. But if the protein begins to build up, it can accumulate into plaques in the brain, stick to neurons, and cause neurological damage, contributing to the development and progression of Alzheimer's disease. For this reason, there is an urgent need for simple screening tests that can predict a person's risk for Alzheimer's disease long before plaque buildup occurs. At present, the only methods that are viable for detecting amyloid beta in the brain are using positron emission tomography (PET) scanning or a spinal tap. However, PET scanning is expensive and "not widely available," and a spinal tap is invasive and requires a "specialized medical p...